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[163] A cartridge may contain 0 to 20 mg of nicotine

Following a rigorous science-based review of the premarket tobacco product applications (PMTAs) submitted by the company, the agency determined that authorizing these reduced nicotine products for sale in the US is appropriate for the protection of the public health because of, among several key considerations, the potential to reduce nicotine dependence in addicted adult smokers, who may also benefit from decreasing nicotine exposure and cigarette consumption

The symptoms, which include bouts of vomiting and abdominal pain that lasts for days, are so intense that they can leave sufferers thinking that theyre dying

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For some, the only way to relieve themselves from these negative feelings and emotions is to smoke a number of cigarettes until they no longer feel stressed or anxious